Research Publications

2018

1) Wang, W., Lorion, M., Shah, J., Kapdi, A. R., Ackermann, L. Late stage peptide diversification by position-selective C-H activation. Accepted Angew. Chem. Int. Ed. 2018.

2) Murthy Bandaru, S., Bhilare, S., Chryosochos, N., Gayakhe, V., Trentin. I., Schulzke, C., Kapdi, A. R.*, Pd/PTABS: Catalyst for Room Temperature Amination of Heteroarenes. Org. Lett. 2018, 20, 473-476. 

3) Ardhapure, A. Kapdi, A. R., Borozdina, Y., Sanghvi, Y. S., Schulzke, C. Crystal Structure of 8-(4-Methylphenyl)-2'-deoxyadenosine. Acta Crystallographica E. 2018, E74, 1-5.

4) Wong, S. M., Choy, P. Y., Kapdi, A. R.,* Kwong, F. Y.,* Recent Developments of Palladium-Catalysed Non-Directed Coupling of (Hetero)arenes C-H Bond with C-Z (Z = B, Si, Sn, S, N, and H) bonds. Org. Chem. Front. 2018, 5, 288-321. 

5) Bandaru, S. M., Kapdi, A. R. and Schuzlke, C. Crystal structure of 4-(Pyrazin-2-yl)morpholine. Acta Crystallographica E. 2018, E74, 137-140.

6) Gayakhe, V., Bhilare, S., Yashmeen, A., Kapdi, A. R.,* Fairlamb, I. J. S. In Transition Metal-Catalysed Modifications of Nucleosides: Palladium-Catalyzed Modification of Nucleosides, Nucleotides and Oligonucleotides. Volume 2: Latest Trends in Palladium Chemistry) Eds. A. R. Kapdi, D. Maiti, Y. S. Sanghvi. Elsevier, New York, 2018 pgs 167-195. 

7) Ardhapure, A. V., Gholap, A., Kapdi, A. R.,* Schulzke, C. In Stille Cross-Coupling Reaction: Early years to the current state-of the art..: Palladium-Catalyzed Modification of Nucleosides, Nucleotides and Oligonucleotides. Volume 2: Latest Trends in Palladium Chemistry) Eds. A. R. Kapdi, D. Maiti, Y. S. Sanghvi. Elsevier, New York, 2018 Pgs 19-36.

8) Kapdi, A. R.,* Rajput, S., Patwardhan, A. V. Dendritic Polymers and Multifunctional Supports. "Applications of One Dimensional Nanomaterials" Ed. Chaughule, R. S. American Scientific Publishers, USA. 2018.

9) Sanghvi, Y. S., Kapdi, A. R. In Future of Drug Discovery: Importance of modified nucleosides, nucleotides and oligonucleotides: Palladium-Catalyzed Modification of Nucleosides, Nucleotides and Oligonucleotides. Volume 2: Latest Trends in Palladium Chemistry) Eds. A. R. Kapdi, D. Maiti, Y. S. Sanghvi. Elsevier, New York, 2018 pgs 1-18.

10) Bangde, P., Prajapati, D., Dandekar-Jain, P., Kapdi, A. R. New Water soluble N-Heterocyclic carbene palladium complexes as promising anti-tumouragents: investigating DNA and protein interactions. Chem. Select, 2018, 3, 5709-5716. 

11) Sable, V., Maindan, K., Bhilare, S., Kapdi, A. R., Chrysochos, N., Schulzke, C. An Active Palladium Colloidal Catalyst For the Selective Oxidative Heterocoupling of (Hetero)Aryl Boronic Acids. Chem. Asian J. 2018 as an invited article for the themed issue ‘Homogeneous Catalysis from Asia: Emerging scientists’. 

12) Gupta, G., Girase, T., Kapdi, A. R. Diels-Alder reactions in Ionic Liquids: Encyclopedia of ionic Liquids. Springer, 2019. Accepted

13) Bhilare, S., Bandaru, S., Kapdi, A. R., Sanghvi, Y. S., Schulzke, C. Pd/PTABS: An Efficient Water Soluble Catalytic System for the Amination of 6-Chloropurine Ribonucleoside and Synthesis of Alogliptin. Accepted Curr. Protoc. Nucleic Acids Chem. 2018.

2017

  1. Lorion, M. M., Maindan, K., Kapdi, A. R.,* Ackermann, L.* Heteromultimetallic Catalysis for Sustainable Organic Syntheses. Chem. Soc. Rev. 2017, 46, 7399-7420.
  2. Sable, V., Maindan, K., Shejwalkar, P., Hara, K., Kapdi, A. R.* Active Palladium Colloids via Palladacycle Degradation as Efficient Catalysts for Oxidative Homocoupling and Cross-Coupling of Aryl Boronic Acids. ACS Omega, 2017, 2, 204-217. 
  3. Gayakhe, V., Gholap, A., Kapdi, A. R.* In Mechanistic/ Organometallic Aspects of Palladium Catalyzed C–H Bond Functionalization.: Strategies for Palladium-Catalyzed Non-Directed and Directed C-H Bond Functionalization. Volume 1: Latest Trends in Palladium Chemistry) Eds. A. R. Kapdi, D. Maiti, Elsevier, New York, 2017, pp 417-452.  
  4. Kapdi, A. R.,* Maiti, D.* Dey, A. Introduction to Non-directed and Directed C-H bond functionalisation: Strategies for Palladium-Catalyzed Non-Directed and Directed C-H Bond Functionalization. (Volume 1: Latest Trends in Palladium Chemistry) Eds. Kapdi A. R., Maiti, D. Elsevier, New York, 2017, pp 1-8. 
  5. Fairlamb, I. J. S., Kapdi, A. R.* In Directed C-H bond functionalization strategies for synthesis.: Strategies for Palladium-Catalyzed Non-Directed and Directed C-H Bond Functionalization. Volume 1: Latest Trends in Palladium Chemistry) Eds. A. R. Kapdi, D. Maiti, Elsevier, New York, 2017, pp 9-48. 
  6. Dhangar, G., Serrano, J. L., Schulzke, C., Gunturu, K. C., Kapdi, A. R.* Palladacycle-Catalyzed Triple Suzuki Coupling Strategy for the Synthesis of Anthracene Based OLED Emitters. ACS Omega, 2017, 2, 3144-3156. 
  7. Gholap, A., Maity, S., Maiti, D.,* Schulzke, C., Kapdi, A. R.* Synthesis of 2,3-disubstituted quinazolinones via intramolecular Cu-catalysed CSP3-H activation/cyclisation. Org. Biomol. Chem., 2017, 15, 7140-7146. 
  8. Gaykhe, V., Kapdi, A. R., Borozdina, Y., Schulzke, C.* Crystal Structure of 5-(Dibenzofuran-4-yl)-2'-deoxyuridine. Acta Crystallographica E. 2017. E73, 1493-1496.   

2016

  1. Gayakhe, V., Ardhapure, A., Kapdi,  A. R.,* Sanghvi, Y. S., Serrano, J. L., Garcia, L., Perez, J., Garcia, J., Fischer, C., Schulzke, C. Water soluble Pd-imidate complexes: Broadly applicable catalysts for the synthesis of chemically modified nucleosides via Pd-catalysed cross-coupling. J. Org. Chem. 2016, 81, 2713-2729. 
  2. Gayakhe, V., Ardhapure, A., Kapdi,  A. R.,* Sanghvi, Y. S., Serrano, J. L., Schulzke, C. C-C Bond Formation: Synthesis of C5 substituted Pyrimidine and C8 Substituted Purine Nucleosides Using Water Soluble Pd-imidate Complex. Current Protocols in Nucleic Acid Chemistry. 2016, 65, 1.37.
  3. Serrano, J. L., Pérez, J. García, L., Pérez, E., Sánchez, G., Kapdi, A. R.* A convenient route to prepare mono- and dinuclear 2-Benzoylpyridine palladacycles with imidate ligands.  J. Organomet. Chem. 2016, 814, 57-62. 
  4. Bhilare, S., Gayakhe, V., Ardhapure, A., Sanghvi, Y. S., Schulzke, C., Borozdina, Y., Kapdi, A. R.* ‘Novel Water-Soluble Phosphatriazenes: Versatile Ligands for Suzuki-Miyaura, Sonogashira and Heck Reactions of Nucleosides’ RSC Adv. 2016, 6, 83820.  

2015

  1. Kapdi, A. R.,* Ardhapure, A., Sanghvi, Y. S. Modulation of the Electronic Properties of Non-innocent (E,E)-Dibenzylideneacetone for Palladium(0)-Mediated Heck-Alkenylation of 5-Iodo-2’-deoxyuridine and Scale-up Studies. Synthesis 2015, 47, 1163-1169. 
  2. Serrano, J. L.,* Perez, J., Garcia, L., Sanchez, G., Garcia, J., Lozano, P., Zende, V., Kapdi, A. R.* N-heterocyclic-carbene complexes readily prepared from di--hydroxo-palladacycles catalyze the Suzuki arylation of 9-bromophenanthrene. Organometallics 2015, 34, 522. 
  3. Kapdi,  A. R.,*  Ardhapure, A., Sanghvi, Y. S., Serrano, J. L.,Sánchez, J., García, J., Lozano, P. Pd-imidate complexes as recyclable catalysts for the synthesis of C5-alkenylated pyrimidine nucleosides via Heck cross-coupling reaction. RSC Advances. 2015, 5, 24558-24563. 
  4. Kapdi,  A. R.,* Gayakhe, V., Sanghvi, Y. S., Fairlamb, I. J. S. Catalytic C–H Bond Functionalisation of Purine and Pyrimidine Nucleosides: A Synthetic and Mechanistic Perspective.  Chem. Commun., 2015, 51, 11944-11960. (Inside cover page article)
  5. Prajapati, D., Schulzke, C., Kindermann, M., Kapdi,  A. R.,* Selective Palladium-Catalysed Arylation of Dibromopyridine Using N-Heterocyclic Carbene Ligands. RSC Advances, 2015, 5, 53073-53085. 
  6. Zende, V., Schulzke, C., Kapdi,  A. R.,*Pincer CNC bis-N-Heterocyclic Carbenes: Robust Ligands for Palladium-Catalysed Suzuki-Miyaura Arylation of BromoAnthracene and Related Substrates. Org. Chem. Front. 2015, 2, 1397-1410.  

2014-2013

  1. Kapdi, A. R., Chaughule, R. S., Nanotechnology: Bridging Aspects of Catalysis, Energy and Drug Delivery Contents and Scope: Nanoparticles for Catalysis, Energy and Drug Delivery (Eds.: R. G. Chaughule and A. R. Kapdi) American Scientific Publishers, 2014
  2. Kapdi, A. R.* In Metal Nanoparticles: Green Catalysis in Water- Nanoparticles for Catalysis, Energy and Drug Delivery (Eds.: R. G. Chaughule and A. R. Kapdi) American Scientific Publishers, 2014
  3. Kapdi, A. R.*, Organometallic Aspects of Transition-Metal Catalysed Regioselective C–H Bond Functionalisation of Arenes and Heteroarenes. Dalton Trans. 2014, 43, 3021-3034 (Invited Article). 
  4. Kapdi, A. R.,* Gayakhe, V., Sanghvi, Y. S., García, J., Lozano, P., da Silva, I., Pérez, J. and Luis Serrano, J. New water soluble Pd-Imidate complexes as highly efficient catalysts for the synthesis of C5-arylated pyrimidine nucleosides via Suzuki-Miyaura cross-coupling. RSC Advances 2014, 4, 17567-17572. 
  5. Kapdi A. R.,* Fairlamb, I. J. S. Anti-cancer palladium complexes: a focus on PdX2L2 and palladacycles. Invited article to Chem. Soc. Rev. 2014, 43, 4751-4777. 
  6. Kapdi, A. R., Dhangar, G., Serrano, J. L., Perez, J., Garcia, L., Fairlamb, I. J. S.* [Pd(C^N)(X)(PPh3)] palladacycles react with 2,4,6-trifluorophenyl boronic acid without exogenous base to give stable transmetallation products of the type [Pd(C^N)(2,4,6-F3C6H2)(PPh3)]. Chem. Commun. 2014, 50, 9859. 
  7. Kapdi, A. R.,* Prajapati, D. Regioselective Palladium-Catalysed Cross-Coupling Reactions: A Powerful Synthetic Tool. Invited review for Prof. Richard Taylor’s 65th Birthday commemoration. RSC Advances. 2014, 4, 41245. 
  8. Kapdi, A. R.,* Dhangar, G., Serrano, J. L., Haro, J. D., Lazano, P., Fairlamb, I. J. S. [Pd(Phbz)(X)(PPh3)] palladacycles promote the base-free homocoupling of arylboronic acids in air at room temperature. RSC Advances. 2014, 4, 55305-55312.   Shah, P. A.; Garcia, J.; Santana, M. D.; Serrano, J. L.; Naik, M.; Pednekar, S.; Kapdi, A. R*. [Pd(PPh3)2(Saccharinate)2]- General Catalyst for Suzuki-Miyaura, Negishi cross-coupling and C-H bond functionalization of coumaryl and pyrone substrates. Tetrahedron 2013, 69, 1446-1453. (Cited in Chem Inform, 2013, 44, 136) 
  9. Kapdi, A. R.,* Fairlamb, I. J. S.* Synthesis of Macrocyclic Ketones Exploiting Palladium-Catalyzed Activation of Carboxylic Acids as an Enabling Step. New J Chem. 2013, 37, 961-964 (cited in Chem. Inform, 2013, 44). 
  10. Kapdi, A. R., Whitwood, A. C., Burns, M. J., Fairlamb, I. J. S*. Dinuclear palladium(0) complexes containing symmetrical and unsymmetrical aryl substituted E,E- dibenzylidieneacetone ligands: The importance of aryl substituents and 1,4-dien-3-one conformation. J. Am. Chem. Soc. 2013, 135, 8388-8399. 
  11. A. R. Kapdi,* C. Jain, T. Padte, U. Shevde, S. Pednekar, C. Fischer and C. Schulzke, Tween-80: A Bio-degradable and Recyclable Phase Transfer Catalyst for Microwave Assisted Synthesis of Highly Substituted Dicoumarols. Int. J. Green Chem. Bioprocess 2013, 3, 17-23. 
  12. A. R. Kapdi,* A. Karbelkar, M. Naik, S. Pednekar, C. Fischer, C. Schulzkec and M. Tromp: Efficient Synthesis of coumarin based Tetra and Pentacyclic rings using Phospha-Palladacycles. RSC Advances 2013, 3, 20905-20912..   

2012-2004

  1. Beeby*, A., Bettington, S., Fairlamb*, I. J. S., Goeta, A. E., Kapdi A. R. and Thompson, A. L.: A new precatalyst for the Suzuki reaction- a pyridyl-bridged dinuclear palladium complex as a novel source of mono-ligated palladium(0). New. J. Chem. 2004, 28, 600-605. (Cited in Chem Inform, 2004, 35, 103) 
  2. Fairlamb*, I.J.S., Kapdi, A. R.,. Lynam, J. M., Taylor*, R. J. K. and Whitwood, A. C.: Bis (triphenyl-phosphine) palladium (П) Succinimide- a new precatalyst for Suzuki cross coupling. Tetrahedron 2004, 60, 5711-5718. (Cited in Chem Inform, 2004, 35, 94) 
  3. Chaignon, N., Fairlamb*, I.J.S.,. Kapdi, A.R., Taylor*, R.J.K. and Whitwood, A.C.: Bis (triphenyl-phosphine) palladium (II) Succinimide an easily prepared precatalyst for Suzuki-Miyaura coupling reactions. J. Mol. Cat. A: Chem. 2004, 219, 191-199. (cited 11 times
  4. Fairlamb*, I.J.S., Kapdi, A.R. and Lee, A.: η2-dba complexes of palladium (0): electron rich dba ligands enhance the reactivity of ‘PdLn’ catalyst species in Suzuki-Miyaura coupling. Org. Lett. 2004, 6, 4435-4438. (78 citations
  5. Fairlamb*, I.J.S., Kapdi, A.R., Lee, A., Sanchez, G., Lopez, G., Serrano*, J. L., Garcia, L., Perez, J. and Perez. E.: Mono- and binuclear cyclometallated palladium(II) complexes containing bridging (N, O-) and terminal (N-) imidate ligands: Air stable, thermally robust and recyclable catalysts for cross-coupling processes. Dalton Trans. 2004, 3970-3981. (cited 27 times)
  6. Crawforth, C. M., Burling, S., Fairlamb*, I.J.S., Kapdi, A.R., Taylor*, R.J.K. and Whitwood, A. C.: Oxidative addition of N-halosuccinimides to palladium (0): The discovery of neutral palladium (II) imidate complexes which enhance Stille coupling of allylic and benzylic halides. Tetrahedron 2005, 61, 9736-9751. (Cited in Chem Inform, 2006, 37, 57) 
  7. Fairlamb*, I. J. S., Kapdi, A. R., Serrano, J. L., Taylor R. J. K. and Sanchez, G.: Air stable, phosphine-free anionic palladacyclopentadienyl catalysts: Remarkable halide and pseudohalide effects in Stille coupling. Adv. Synth. Cat. 2006, 348, 405-412. (Cited in Chem Inform, 2006, 37, 52) 
  8. Macé, Y., Kapdi, A. R., Fairlamb*, I. J. S. and Jutand*, A.: Influence of the dba substitution on the reactivity of Pd(0) complexes generated from Pd02(dba-n,n' Z)3 or Pd0(dba-n,n' Z)2 and PPh3 in oxidative addition with iodobenzene. Organometallics 2006, 25, 1795-1800. (cited 31 times
  9. Fairlamb*, I. J. S., Kapdi, A. R., Lee, A. F., McGlacken, G. P., Weissburger F., de Vries, A. H. M. and Schmieder-van de Vondervoort, L.: Exploiting non-innocent (E,E)-dibenzylidene acetone (dba) effects in palladium(0) mediated cross-coupling reactions: modulation of the electronic properties of dba affects catalyst activity and stability in ligand and ligand-free reaction systems. Chem. Eur. J. 2006, 12, 8750 – 8761. (Cited 40 times
  10. Fairlamb*, I. J. S. and Kapdi, A. R.: Synthesis of substituted dibenzylidene acetone (dba) derivatives. Synthetic pages 2004, 221.  
  11. Burns, M.J., Fairlamb*, I.J.S., Kapdi, A. R., Sehnal, P. and Taylor*, R. J. K.: A simple palladium(II) precatalyst for Suzuki-Miyaura couplings: efficient reactions of benzylic, aromatic and heteroaromatic coupling partners. Org. Lett. 2007, 9, 5397-5400. (Cited in Chem Inform, 2008, 39, 93)  
  12. Ackermann*, L., Vicente, R., Kapdi, A. R.: Review Article- Transition Metal-Catalyzed Direct Arylations of (Hetero)Arenes via C–H Bond Cleavage. Angew. Chem. Int. Ed. 2009, 48, 9792-9827; Angew. Chem. 2009, 121, 9976–10012. (Cited 209 times) (Cover Page Article; Cited in Chem Inform, 2010, 41, 243) 
  13. Ackermann*, L., Weschler, C., Kapdi, A. R., Althammer, A.: Air-Stable Diaminophosphine Sulfides as Preligands for Nickel-Catalyzed Cross-Couplings of Fluoroarenes. Synlett, 2010, 294-298. (Cited in Chem Inform, 2010, 41, 76 and Synfacts
  14. Ackermann*, L., Potukuchi, H., Kapdi, A. R., Schulzke, C.: Efficient Kumada Cross-Coupling of 2-Pyridyl Grignard Reagent with Aryl Bromides. Chem. Eur. J. 2010, 16, 3300-3303. (Cited in Chem Inform, 2010, 41, 158) 
  15. Ackermann*, L., Kapdi, A. R., Schulzke, C.: Air-Stable Secondary Phosphine Oxide or Chloride (Pre)Ligands for Cross-Couplings of Unactivated Alkyl Chlorides. Org. Lett. 2010, 12, 2298–2301. (Cited on Organic Chemistry Portal http://www.organic-chemistry.org/abstracts/lit2/911.shtm; Cited in Chem Inform, 2010, 41, 47))
  16. Ackermann*, L., Kapdi, A. R., Kornhass, C.; Fenner, S., Schulzke, C.: Highly Active Air-Stable Dimeric Palladium(II)- Phosphonite Complex for Efficient Kumada-Corriu Cross-Coupling of (Hetero)Aryl and Alkenyl Tosylates. Chem. Eur. J. 2011, 17, 2965-2971. (Cited in Chem Inform, 2011, 42, 86)  
  17. Ackermann*, L.; Barfusser, S.; Kornhass, C.; Kapdi, A. R. C-H bond Arylations and Benzylations on Oxazol(in)es with a Palladium Catalyst of a Secondary Phosphine Oxide. Org. Lett. 2011, 13, 3082-3085. (Cited in Chem Inform, 2011, 42, 131) 
  18. Kapdi*, A. R.; Taylor, R. J. K.; Fairlamb*, I. J. S. Highly Regio- and Chemoselective Palladium(0)-Mediated Allylic Substitution of Difunctional Allylic Halides with Phenols. Tetrahedron Lett. 2010, 51, 6378-6380. 
  19. Sirisha, P.; Pednekar*, S.; Kapdi, A. R. Facile p-TSA Catalyzed One Pot Synthesis of Tetrahydropyrimidinones Derivatives in Water and Under Solventless Condition. Bull. Catal. Soc. India 2010, 9, 138-141.  
  20. Kapdi*, A. R. Innocent Or Non-Innocent: Towards Understanding The Role Of DBA In Palladium(0) Mediated Cross-Coupling Reactions. Review article in Bull. Catal. Soc. India 2010, 9, 12-28. 
  21. Sánchez*, G.; García, J.; Martínez, M.; Pérez, J.; García, L.; Serrano, J. L.; Kapdi, A R. Bis(imidate)palladium(II) complexes with labile ligands. Mimics of classical precursors? Dalton Trans. 2011, 40, 12676-12689. (Cover Page Article
  22. Sirisha, P.; Pednekar*, S.; Kapdi, A. R.; Naik, M. Facile One Pot Synthesis of Pyranobenzopyran and Their Derivatives. J. Chem. Sci. 2011, 123, 667-672. (cited in Chem Inform, 2012, 43, 123) 
  23. Santana, M. D.; García-Bueno, R.; García, G.; Sánchez, G.; García, J.; Naik, M.; Pednekar, S.; Kapdi, A. R.*; Pérez, J.; García, L.; Pérez L.; Serrano, J. L*. A new route towards cyclopalladated complexes with saccharinate ligands: luminescence properties and catalytic activity. Dalton Trans. 2012, 41, 3832-3842. 
  24. Kapdi, A. R.* In Organometallic Aspects of C-H bond activation/functionalization: Specialist Periodical Reports- Organometallic Chemistry (Eds.: I. J. S. Fairlamb) RSC, Organomet. Chem. 2012, 38, 47-73 (cited in Chem Inform, 2013, 44). 
  25. Ackermann*, L., Kapdi, A. R., Kozhuskov, S. I., Potukuchi, H. In Synthesis via C-H Bond Functionalization: In Handbook of Green Chemistry Series (Green Synthesis) (Ed.: C. J. Li) Wiley, New Weinheim, 2012, 259-305. 
  26. Kapdi, A. R.*, Fairlamb, I. J. S.* In Alkynylzinc and Other Cross-Coupling: C-C Cross-Coupling and Heck Reactions. Science of Synthesis-Houben Weyl Series (Eds.: G. Molander) Thieme, Invited Book Chapter 2012. 
  27. Serrano, J. L.,* Perez, J., Garcia, L., Sanchez, G., Garica, J., Tyagi, K., Kapdi, A. R.* New Phospha-Palladacyles: Efficient Catalysts for Formylation of Aryl Chlorides. RSC Advances 2012, 2, 12237-12244.